Original Papers

N. Hosokawa, H. Kushige and H. Iwasaki (2013)
"Attenuation of the posttranslational oscillator via transcription?translation feedback enhances circadian-phase shifts in Synechococcus"
Proc. Natl. Acad. Sci. USA, in press (Eearly Edition, August 12)

Kushige, H., Kugenuma, H., Matsuoka, M., Ehira, S., Ohmori, M., Iwasaki, H.* (2013)
"Genome-wide and heterocyst-specific circadian gene expression in the filamentous cyanobacterium, Anabaena sp. PCC 7120".
J. Bacteriol. 195: 1276-1284

M. Hanaoka*, N. Takai, N. Hosokawa, M. Fujiwara, Y. Akimoto, N. Kobori, H. Iwasaki, T. Kondo, K. Tanaka (2012)
"RpaB, another response regulator operating circadian clock-dependent transcriptional regulation in Synechococcus elongatus PCC 7942"
J. Biol. Chem., 287: 26321-26327
-プレスリリース:千葉大学 (pdf),早稲田大学から

N. Hosokawa, T. Hatakeyama, T. Kojima, Y. Kikuchi, H. Ito and H. Iwasaki* (2011)
"Circadian transcriptional regulation by the posttranslational oscillator without de novo clock gene expression in Synechococcus"
Proc. Natl. Acad. Sci. USA, 108: 15396-15401. OPEN ACCESS ARTICLE

H. Asai, S. Iwamori, K. Kawai, S. Ehira, J. Ishihara, K. Aihara, S. Shoji, H. Iwasaki* (2009)
"Cyanobacterial cell lineage analysis of the spatiotemporal hetR expression profile during heterocyst pattern formation in Anabaena sp. PCC 7120" 
PLoS ONE, 4(10): e7371 (October 12, 2009)

H. Ito, M. Mutsuda, Y. Murayama, J. Tomita, N. Hosokawa, K. Terauchi, C. Sugita, M. Sugita, T. Kondo, H. Iwasaki* (2009)
"Cyanobacterial daily life with Kai-based circadian and diurnal genome-wide transcriptional control in Synechococcus elongatus"
Proc. Natl. Acad. Sci. USA, 106:14168-14173 (June 30, 2009)

H. Tozaki, T. Kobe, K. Aihara, H. Iwasaki* (2008)
"An attempt to reveal a role of a transcription/translation feedback loop in the cyanobacterial KaiC protein-based circadian system by using a semi-synthetic method"
Int. J. Bioinform. Res. Appl. , 4: 435-444

S.R. Mackey, JS. Cho, Y. Kitayama, H. Iwasaki, G. Dong, S.S. Golden (2008)
"Proteins found in a CikA-interaction assay link the circadian clock, metabolism, and cell division in Synechococcus elongatus"
J. Bacteriol., 190: 3738-3746

A. Seki, M. Hanaoka, Y. Akimoto, S. Masuda, H. Iwasaki, K. Tanaka (2007)
"Induction of a group 2 sigma factor, RpoD3, by high light and the underlying mechanism in Synechococcus elongatus PCC 7942"
J. Biol. Chem., 282: 36887-36894

F. Miyoshi, Y. Nakayama , K. Kaizu, H. Iwasaki, M. Tomita (2007)
"A mathematical model for the Kai-protein-based chemical oscillator and clock gene expression rhythms in cyanobacteria "
J. Biol. Rhythms, 22: 69-80

N. Takai, M. Nakajima, T. Oyama, R. Kito, C. Sugita, M. Sugita, T. Kondo, H. Iwasaki* (2006)
"A KaiC-associating SasA-RpaA two-component regulatory system as a major circadian timing mediator in cyanobacteria "
Proc Natl Acad Sci USA, 103: 12109-12114

H. Kageyama, T. Nishiwaki, M. Nakajima, H. Iwasaki, T. Oyama, T. Kondo (2006)
"Cyanobacterial circadian pacemaker: Kai protein complex dynamics in the KaiC phosphorylation cycle in vitro"
Molecular Cell, 23: 161-171

M. Nakajima, K. Imai, H. Ito, T. Nishiwaki, Y. Murayama, H. Iwasaki, T. Oyama, T. Kondo (2005)
"Reconstitution of circadian oscillation of cyanobacterial KaiC phosphorylation in vitro"
Science 308, 5720: 414-415

Tomita J, Nakajima M, Kondo T, Iwasaki H* (2005)
"No transcription-translation feedback in circadian rhythm of KaiC phosphorylation."
Science 307, 5707: 251-254

T. Nishiwaki, Satomi Y, Nakajima M, Lee C, Kiyohara R, Kageyama H, Kitayama Y, Temamoto M, Yamaguchi A, Hijikata A, Go M, Iwasaki H, Takao T, Kondo T. (2004)
"Role of KaiC phosphorylation in the circadian clock system of Synechococcus elongatus PCC 7942."
Proc Natl Acad Sci USA 101:13927-32

Imai K, Nishiwaki T, Kondo T, Iwasaki H* (2004)
"Circadian rhythms in the synthesis and degradation of a master clock protein KaiC in cyanobacteria."
J Biol Chem 279:36534-9

Nakahira Y, Katayama M, Miyashita H, Kutsuna S, Iwasaki H, Oyama T, Kondo T (2004)
"Global gene repression by KaiC as a master process of prokaryotic circadian system."
Proc Natl Acad Sci USA 101: 881-885

Kitayama Y, Iwasaki H, Nishiwaki T, Kondo T (2003)
"KaiB functions as an attenuator of KaiC phosphorylation in the cyanobacterial circadian clock system."
EMBO J. 22:2127-34

Kageyama H, Kondo T, Iwasaki H* (2003)
"Circadian formation of clock protein complexes by KaiA, KaiB, KaiC, and SasA in cyanobacteria."
J Biol Chem. 278:2388-95

Iwasaki H*, Nishiwaki T, Kitayama Y, Nakajima M, Kondo T (2002) *corresponding author
"KaiA-stimulated KaiC phosphorylation in circadian timing loops in cyanobacteria."
Proc Natl Acad Sci USA 99:15788-93

Taniguchi Y, Yamaguchi A, Hijikata A, Iwasaki H, Kamagata K, Ishiura M, Go M, Kondo T (2001)
"Two KaiA-binding domains of cyanobacterial circadian clock protein KaiC."
FEBS lett. 496: 86-90

Iwasaki H, Williams SB, Kitayama Y, Ishiura M, Golden SS, Kondo T (2000)
"A KaiC-interacting sensory histidine kinase, SasA, necessary to sustain robust circadian oscillation in cyanobacteria."
Cell 101: 223-233

Nishiwaki T, Iwasaki H, Ishiura M, Kondo T (2000)
"Nucleotide binding and autophosphorylation of the clock protein KaiC as a circadian timing process of cyanobacteria."
Proc Natl Acad Sci USA 97: 495-499

S Hirota, K Hayamizu, T Okuno, M Kishi, H Iwasaki, T Kondo, T Hibino, T Takabe, T Kohzuma, O Yamauchi (2000)
"Spectroscopic and electrochemical studies on structural change of plastocyanin and its tyrosine 83 mutants induced by interaction with lysine peptides"
Biochemistry, 39: 6357-6364

Iwasaki H, Taniguchi Y, Ishiura M, Kondo T (1999)
"Physical interactions among circadian clock proteins, KaiA, KaiB and KaiC, in cyanobacteria."
EMBO J 18: 1137-1145

NJ Cosper, C Stalhandske, H Iwasaki, T Oshima, R Scott, T Iwasaki (1999)
"Structural conservation of the isolated zinc site in archaeal zinc-containing ferredoxins as revealed by X-ray absorption spectroscopic analysis and its evolutionary implications."
J. Biol. Chem.274: 23160-23168

Ishiura, M, Kutsuna S, Aoki S, Iwasaki H, Andersson CR, Tanabe A, Golden SS, Johnson CH, Kondo T (1998)
"Expression of a gene cluster kaiABC as a circadian feedback process in cyanobacteria."
Science 281: 1519-1523

M Takahashi, H. Iwasaki, T. Niimi, O Yamashita, T Yaginuma (1998)
"Changing profiles of mRNA levels of Cdc2 and a novel Cdc2-related kinase (Bcdrk) in relation to ovarian development and embryonic diapause of Bombyx mori."
Appl. Entomol. Zool. 33: 551-559

H Iwasaki, M Takahashi, T Niimi, O Yamashita, T Yaginuma (1996)
"Cloning of cDNAs encoding Bombyx homologues of Cdc2 and Cdc2-related kinase from eggs."
Insect Mol. Biol.6: 131-141


Invited Review Articles

Iwasaki H (2009)
"A posttranslational chemical circadian oscillator in cyanobacteria"
Systems Biology: The Challenge of Complexity (Eds. Nakanishi,S., Kageyama,R., Watanabe,D), Springer

Iwasaki H (2009)
"Factors involved in transcriptional output from the Kai-protein-based circadian oscillator"
Bacterial Circadian Programs (Eds. J. Ditty, S. Mackey, C.H. Johnson), Springer

Iwasaki H, Kondo T. (2004)
"Circadian timing mechanism in the prokaryotic clock system of cyanobacteria."
J. Biol. Rhythms 19: 436-444

Iwasaki H, Kondo T. (2002)
"Histidine kinases in the cyanobacterial circadian system"
Histidine Kinases (Eds. M. Inouye and R. Dutta), Academic Press

Iwasaki H, Kondo T (2000)
"The current state and problems of circadian clock studies in cyanobacteria."
Plant Cell Physiol. 41: 1013-1020

Iwasaki H, Dunlap JC (2000)
"Microbial circadian oscillatory systems in Neurospora and Synechococcus: models for cellular clocks."
Curr. Opin. Microbiology 3: 189-196